This will be a crucial century in human history, because a Moon or Mars base is likely to exist by 2030 or so and the first culture(s) to make it off the planet in self-sufficient amounts will get a head start and so will likely dominate the rest of human history in an even more extreme way than European cultures now dominate in the Americas.
Which cultures will it be? The lead contenders so far are the Chinese, the Russians and the US. The Russians are the smaller country by population, but are consistently capable, and have a kind of destiny about them - it was Tsiolkovski who started it all. The American record is unsurpassed (eg: the Moon landing) and one should never underestimate their talent for inventing, and importing, new and quicker ways to do things - and then throwing them away in the short term rush for monetary or political gain. The Chinese are coming from behind, but for much of human history they were the most advanced culture, and their traditions have provided them with a huge, talented, population. They are now arguably ahead of the US because they have an active manned program. The technologically-gifted Japanese, the clever Indians and Europe with its great tradition of logic & science are also contenders. The more the merrier..
As is usual with life, the cultures that reproduce (ie: set up a self-sufficient colony off planet, that has the potential to grow) will be the ones that push outwards into deep space and will eventually dominate history. I would not like to even predict which cultures these should be. Nature, in its wisdom, will decide in a Darwinian way. The ones with the most desire and capability for space travel will also be the best ones to take humans (or whatever we become) across the galaxy more quickly.
There is a deep imperative in all life to grow and spread. Look at nature and the huge effort all life makes to reproduce. A stay-at-home mentality, stagnation and extinction would be a huge waste of millenia of human struggle & history. We should add our unique voice, whatever its accent, to whatever is going on out there.